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Community Engaged Research to Address Health Disparities in Systemic Lupus Erythematosus


Arthritis Care Res (Hoboken). 2020 Aug 25. doi: 10.1002/acr.24432. Online ahead of print.

R Ezequiel Borgia 1 2, Graciela S Alarcón 3 4

Author Information

1 Department of Pediatrics, Division of Allergy, College of Medicine, University of Florida, Immunology & Rheumatology, Gainesville, Florida, USA.

 2 Department of Health Outcomes & Biomedical Informatics, College of Medicine, University of Florida, Gainesville, Florida, USA.

3 Department of Medicine, Division of Clinical Immunology and Rheumatology, School of Medicine, The University of Alabama, Birmingham, Alabama, USA.

4 Department of Medicine, Universidad Peruana Cayetano Heredia, Lima, Perú.


Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by evidence of autoantibodies and multiorgan system involvement leading to significant physical and functional disability. The reported incidence and prevalence of SLE in the US vary by region but are estimated to be around 5.5 per 100,000 per year and 72.8 per 100,000 persons, respectively. Several social determinants of health including educational level, health insurance, household income, social support as well as environmental and occupational exposures may impact lupus outcomes.