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Adherence and resource use among psoriasis patients treated with biologics

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Aleshaki JS1, Cardwell LA1, Muse ME1, Feldman SR1,2,3. Expert Rev Pharmacoecon Outcomes Res. 2018 Dec;18(6):609-617. doi: 10.1080/14737167.2018.1512408. Epub 2018 Sep 10.


Author information 1 a Center for Dermatology Research, Department of Dermatology , Wake Forest School of Medicine , Winston-Salem , NC , USA. 2 b Department of Pathology , Wake Forest School of Medicine , Winston-Salem , NC , USA. 3 c Department of Social Sciences & Health Policy , Wake Forest School of Medicine , Winston-Salem , NC , USA.


The emergence of immune-modulating drugs such as biologics has altered the treatment landscape for psoriasis. However, their use presents high financial costs to patients and healthcare systems. Patient demographic and socioeconomic status may influence adherence to biologic medications and usage of healthcare resources. Areas covered: We performed a systematic literature review to summarize the available evidence pertaining to biologic medication adherence and resource use. PubMed was searched using the terms 'psoriasis and adherence' and 'psoriasis biologics resource use.' Expert commentary: Psoriasispatients utilize many healthcare resources. Adherence rates are typically higher for biologics than for other psoriasis treatment categories. However, adherence rates are still suboptimal.