Abstract Library

The summaries are free for public use. ARTHROS will continue to add and archive summaries of articles deemed relevant to ARTHROS by our Faculty.


Orthopaedic Gene Therapy: Twenty-Five Years On

JBJS Rev. 2021 Aug 26;9(8). doi: 10.2106/JBJS.RVW.20.00220.

Christopher H Evans 1Steve C Ghivizzani 2Paul D Robbins 3


Jellyfish Collagen: A Biocompatible Collagen Source for 3D Scaffold Fabrication and Enhanced Chondrogenicity

Mar Drugs. 2021 Jul 22;19(8):405. doi: 10.3390/md19080405.

Zara Ahmed 1Lydia C Powell 1Navid Matin 1Andrew Mearns-Spragg 2Catherine A Thornton 1Ilyas M Khan 1Lewis W Francis 1


A Single-Blinded Randomized Controlled Trial of Mesenchymal Stem Cell Therapy for the Treatment of Osteoarthritis of the Knee with Active Control

 Stem Cells Regen Med. 2021 Jan 2;17(1):3-17. doi: 10.46582/jsrm.1701002. eCollection 2021.

Joseph J Ruane 1Andrew Ross 2Victoria Zigmont 2Deanna McClure 1Gregg Gascon 2


The Hip Instructional Prehabilitation Program for Enhanced Recovery (HIPPER) as an eHealth Approach to Presurgical Hip Replacement Education: Protocol for a Randomized Controlled Trial

JMIR Res Protoc. 2021 Jul 6;10(7):e29322. doi: 10.2196/29322.

William C Miller 1 2Somayyeh Mohammadi 1 2Wendy Watson 3Morag Crocker 3Marie Westby 3


Home-based rehabilitation programme compared with traditional physiotherapy for patients at risk of poor outcome after knee arthroplasty: the CORKA randomised controlled trial

BMJ Open. 2021 Aug 27;11(8):e052598. doi: 10.1136/bmjopen-2021-052598.

Karen L Barker 1Jonathan Room 2Ruth Knight 3Susan Dutton 3Francine Toye 4Jose Leal 5Nicola Kenealy 6Michael Maia Schlüssel 6Gary Collins 7David Beard 6Andrew James Price 6Martin Underwood 8Avril Drummond 9Sarah Lamb 10 11CORKA Trial group


  • CORKA Trial group

Leon Palmer-WilsonAna GlennonHelen WilsonChristian BrookesDenise HillSusan DowdleHazel BurtJane HarrisonSarah AdcockJustine TheakerGladys Nadar ArulmaniSunil JainMike ReedJonathan RoomGenevieve SimpsonGemma KnightTricia MonroeGareth StephensSarah Rich


Quality of Life Associates With Moderate to Vigorous Physical Activity Following Anterior Cruciate Ligament Reconstruction

J Athl Train. 2021 Jul 30. doi: 10.4085/1062-6050-0670.20. Online ahead of print.

Hope C Davis-Wilson 1Louise M Thoma 2 3Lara Longobardi 4Jason R Franz 5J Troy Blackburn 2 6 7A C Hackney 2 8Brian Pietrosimone 2 6 7


eNAMPT Is Localised to Areas of Cartilage Damage in Patients with Hip Osteoarthritis and Promotes Cartilage Catabolism and Inflammation

Int J Mol Sci. 2021 Jun 23;22(13):6719. doi: 10.3390/ijms22136719.

Ashleigh M Philp 1Sam Butterworth 2Edward T Davis 3Simon W Jones 1


Meta-Analysis of Adipose Tissue Derived Cell-Based Therapy for the Treatment of Knee Osteoarthritis

Cells. 2021 Jun 1;10(6):1365. doi: 10.3390/cells10061365.

Nikhil Agarwal 1Christopher Mak 2Christine Bojanic 2Kendrick To 2Wasim Khan 2


Characterization of individuals with osteoarthritis in the United States and their use of prescription and over-the-counter supplements

Maturitas. 2021 Mar;145:24-30. doi: 10.1016/j.maturitas.2020.12.001. Epub 2020 Dec 5.

Nancy E Lane 1Jasmina Ivanova 2Birol Emir 3Ali Mobasheri 4Morten Georg Jensen 5


Optimization of Lyophilized Hyperacute Serum (HAS) as a Regenerative Therapeutic in Osteoarthritis

Int J Mol Sci. 2021 Jul 13;22(14):7496. doi: 10.3390/ijms22147496.

Isabel Olmos Calvo 1Olga Kuten-Pella 1Karina Kramer 2Ágnes Madár 1Szilvia Takács 1Dorottya Kardos 3Diána Simon 4Szabina Erdö-Bonyár 4Timea Berki 4Andrea De Luna 2Stefan Nehrer 2Zsombor Lacza 5 6


Associations of Comorbid Conditions and Transitions Across States of Knee Osteoarthritis in a Community-Based Cohort

ACR Open Rheumatol. 2021 Jul 1. doi: 10.1002/acr2.11287. Online ahead of print.

Yvonne M Golightly 1Carolina Alvarez 1Liubov S Arbeeva 1Rebecca J Cleveland 1Todd A Schwartz 1Jordan B Renner 1Louise B Murphy 2Leigh F Callahan 1Joanne M Jordan 1Amanda E Nelson 1


The safety and effectiveness of bone marrow concentrate injection for knee and hip osteoarthritis: a Canadian cohort

Regen Med. 2021 Jun 30. doi: 10.2217/rme-2021-0001. Online ahead of print.

Robert Burnham 1 2 3Ashley Smith 2 4David Hart 5 6


A Prospective Randomized Double-Blind Clinical Trial to Assess the Effects of Leukocyte-reduced Platelet-Rich Plasma on Pro-inflammatory, Degradative, and Anabolic Biomarkers after Closed Pilon Fractures

J Orthop Res. 2021 Jun 29. doi: 10.1002/jor.25123. Online ahead of print.

Bradford P Zitsch 1Christopher R James 2Brett D Crist 2Aaron M Stoker 2 3Gregory J Della Rocca 2James L Cook 2 3


Do Narcotic Use, Physical Therapy Location, or Payer Type Predict Patient-Reported Outcomes After Anterior Cruciate Ligament Reconstruction?

Orthop J Sports Med. 2021 Apr 26;9(4):2325967121994833. doi: 10.1177/2325967121994833.eCollection 2021 Apr.

Cleveland Clinic Sports HealthJaret M Karnuta 1Sarah Dalton 1James Bena 1Lutul D Farrow 1Joseph Featherall 1Morgan H Jones 1Anthony A Miniaci 1Richard D Parker 1James T Rosneck 1Paul Saluan 1Greg Strnad 1Kurt P Spindler 1James S Williams 1Sameer R Oak 1


Return to Sport After Hip Resurfacing Arthroplasty

Orthop J Sports Med. 2021 May 6;9(5):23259671211003521. doi: 10.1177/23259671211003521.eCollection 2021 May.

Kyle W Morse 1Ajay Premkumar 1Andrew Zhu 1Rachelle Morgenstern 2Edwin P Su 2


The critical role of Hedgehog-responsive mesenchymal progenitors in meniscus development and injury repair

Elife. 2021 Jun 4;10:e62917. doi: 10.7554/eLife.62917.

Yulong Wei # 1 2Hao Sun # 1 3Tao Gui # 1 4Lutian Yao 1Leilei Zhong 1Wei Yu 1 2Su-Jin Heo 1 5Lin Han 6Nathaniel A Dyment 1Xiaowei Sherry Liu 1Yejia Zhang 1 5 7Eiki Koyama 8Fanxin Long 8Miltiadis H Zgonis 1Robert L Mauck 1 5Jaimo Ahn 1 9Ling Qin 1


The Effect of Platelet-Rich Plasma on the Intra-Articular Microenvironment in Knee Osteoarthritis

Int J Mol Sci. 2021 May 23;22(11):5492. doi: 10.3390/ijms22115492.

Dawid Szwedowski 1 2Joanna Szczepanek 3Lukasz Paczesny 4Jan Zabrzynski 4Maciej Gagat 5Ali Mobasheri 6 7 8 9Slawomir Jeka 10


Impact of educational level and employment status on short-term and long-term pain relief from supervised exercise therapy and education: an observational study of 22 588 patients with knee and hip osteoarthritis

BMJ Open. 2021 Apr 14;11(4):e045156.doi: 10.1136/bmjopen-2020-045156.

Marianne Bakke Johnsen 1 2Ewa Roos 3Dorte Thalund Grønne 3Lars Christian Haugli Bråten 4 2Søren Thorgaard Skou 3 5


Reliability of detection of ultrasound and MRI features of hand osteoarthritis: a systematic review and meta-analysis

Rheumatology (Oxford). 2021 Jun 4;keab470. doi: 10.1093/rheumatology/keab470.Online ahead of print.

Abasiama D Obotiba 1 2Subhashisa Swain 1Jaspreet Kaur 1Michael Doherty 1Weiya Zhang 1Abhishek Abhishek 1 3


A Comparison of Revision Rates for Dislocation and Aseptic Causes Between Dual Mobility and Large Femoral Head Bearings in Primary Total Hip Arthroplasty With Subanalysis by Acetabular Component Size: an Analysis of 106,163 Primary Total Hip Arthroplasties

J Arthroplasty. 2021 May 11;S0883-5403(21)00422-8. doi: 10.1016/j.arth.2021.05.008.Online ahead of print.

Wayne Hoskins 1Roger Bingham 2Chelsea Dyer 3Sophia Rainbird 4Stephen E Graves 5


A Comparison of Bone-Targeted Exercise With and Without Antiresorptive Bone Medication to Reduce Indices of Fracture Risk in Postmenopausal Women With Low Bone Mass: The MEDEX-OP Randomized Controlled Trial

J Bone Miner Res. 2021 May 25. doi: 10.1002/jbmr.4334. Online ahead of print.

Melanie Kistler-Fischbacher 1 2Jedidah S Yong 1 2Benjamin K Weeks 1 2Belinda R Beck 1 2 3



Study Protocol Modeling Evoked Pain in Older African Americans with Knee Osteoarthritis

Nurs Res. 2021 May 5. doi: 10.1097/NNR.0000000000000520. Online ahead of print.

Staja Q Booker 1Angela StarkweatherTodd M ManiniRoland StaudRoger B Fillingim


Obesity, Bariatric Surgery, and Hip/Knee Arthroplasty Outcomes

Surg Clin North Am. 2021 Apr;101(2):295-305. doi: 10.1016/j.suc.2020.12.011.

Katelyn M Mellion 1Brandon T Grover 2


Knee pain trajectories over 18 months in non-Hispanic Black and non-Hispanic White adults with or at risk for knee osteoarthritis

BMC Musculoskelet Disord. 2021 May 5;22(1):415. doi: 10.1186/s12891-021-04284-8.

Alisa J Johnson # 1 2Terrie Vasilopoulos # 3Staja Q Booker 4 5Josue Cardoso 4Ellen L Terry 4 5Keesha Powell-Roach 4 5Roland Staud 6Daniel A Kusko 7Adriana S Addison 7David T Redden 8Burel R Goodin 7Roger B Fillingim 4 9Kimberly T Sibille 4 10


Editorial Commentary: Stem Cells. They Are in the Fat Tissue, Bone Marrow, and Even in the Synovial Fluid of the Knee Joint

Arthroscopy. 2021 Mar;37(3):901-902. doi: 10.1016/j.arthro.2020.12.216.

Erik Hohmann


Editorial Commentary: With Properly Indicated and Performed Surgery, We Can (Hopefully) Prevent Osteoarthritis in Patients With Hip Femoroacetabular Impingement


Arthroscopy. 2021 Mar;37(3):1026-1027. doi: 10.1016/j.arthro.2020.12.179.

Robert W Westermann 1Andrew Schaver 1


Outcomes of Rotator Cuff Repair with Concurrent Microfracture of Focal Glenohumeral Osteoarthritis

J Shoulder Elbow Surg. 2021 Apr 20;S1058-2746(21)00366-9. doi: 10.1016/j.jse.2021.04.008.Online ahead of print.

Brian W Hill 1Arjun M Singh 1Matthew Astolfi 1J Gabe Horneff 1Bradley S Schoch 2Joseph A Abboud 3


The Association Between Cement Viscosity and Revision Risk After Primary Total Knee Arthroplasty

J Arthroplasty. 2021 Jan 27;S0883-5403(21)00092-9. doi: 10.1016/j.arth.2021.01.052.Online ahead of print.

Ronald W B Wyatt 1Richard N Chang 2Kathryn E Royse 2Elizabeth W Paxton 2Robert S Namba 3Heather A Prentice 2


Effect of Telephone Cognitive Behavioral Therapy for Insomnia in Older Adults With Osteoarthritis Pain: A Randomized Clinical Trial

JAMA Intern Med. 2021 Apr 1;181(4):530-538. doi: 10.1001/jamainternmed.2020.9049.

Susan M McCurry 1Weiwei Zhu 2Michael Von Korff 2Robert Wellman 2Charles M Morin 3Manu Thakral 2 4Kai Yeung 2Michael V Vitiello 5


Trends and developments in hip and knee arthroplasty technology

J Rehabil Assist Technol Eng. 2021 Feb 8;8:2055668320952043.doi: 10.1177/2055668320952043. eCollection Jan-Dec 2021.

Martin Marsh 1Simon Newman 1


Person-centred care in osteoarthritis and inflammatory arthritis: a scoping review of people's needs outside of healthcare

BMC Musculoskelet Disord. 2021 Apr 9;22(1):341. doi: 10.1186/s12891-021-04190-z.

Jessica L Fairley 1Maheeka Seneviwickrama 1 2Sabrina Yeh 1Shane Anthony 1Louisa Chou 1Flavia M Cicuttini 1Kaye Sullivan 3Andrew M Briggs 4Anita E Wluka 5


Glenohumeral Osteoarthritis: The Role for Orthobiologic Therapies: Platelet-Rich Plasma and Cell Therapies

JBJS Rev. 2020 Feb;8(2):e0075. doi: 10.2106/JBJS.RVW.19.00075.

Luciano A Rossi 1Nicolás S Piuzzi 1 2Shane A Shapiro 3 4


Utilising the perspectives of patients with lower-limb osteoarthritis on prescribed physical activity to develop a theoretically informed physiotherapy intervention

BMC Musculoskelet Disord. 2021 Feb 8;22(1):155.doi: 10.1186/s12891-021-04036-8.

Matthew Willett 1 2Carolyn Greig 3 4 5Sally Fenton 3 4David Rogers 6Joan Duda 3 4Alison Rushton 7 8


Topical nonsteroidal anti-inflammatory drugs in the treatment of knee osteoarthritis: a systematic review and meta-analysis

Phys Sportsmed. 2021 Mar 4;1-11. doi: 10.1080/00913847.2021.1886573. Online ahead of print.

Dylan G Wolff 1Christy Christophersen 2Symone M Brown 1Mary K Mulcahey 1


Development of a mind body program for obese knee osteoarthritis patients with comorbid depression

Contemp Clin Trials Commun. 2021 Jan 28;21:100720 doi: 10.1016/j.conctc.2021.100720.eCollection 2021 Mar.

Cale A Jacobs 1Ryan A Mace 2Jonathan Greenberg 2Paula J Popok 2Mira Reichman 2Christian Lattermann 3Jessica L Burris 4Eric A Macklin 2Ana-Maria Vranceanu 2



Int J Sports Phys Ther. 2020 Apr;15(2):301-325.

Christopher J CentenoSarah M Pastoriza 1


Generation of human pluripotent stem cell lines (iPSCs) from mesenchymal stem cells (MSCs) from three elderly patients with osteoarthritis

Stem Cell Res. 2020 Apr;44:101721. doi: 10.1016/j.scr.2020.101721. Epub 2020 Feb 14.

Lydiane Pichard 1Jean-Marc Brondelo 2Fabienne Becker 3Romain Desprat 3Frédéric De Ceuninck 4Philippe Pastoureau 4Danielle Noel 2Christian Jorgensen 2Jean-Marc Lemaitre 5


A neural network to predict the knee adduction moment in patients with osteoarthritis using anatomical landmarks obtainable from 2D video analysis

Osteoarthritis Cartilage. 2021 Jan 7;S1063-4584(21)00003-0. doi: 10.1016/j.joca.2020.12.017.Online ahead of print.

M A Boswell 1S D Uhlrich 2L Kidzinski 3K Thomas 4J A Kolesar 5G E Gold 6G S Beaupre 7S L Delp 8


Deep learning enables the automation of grading histological tissue engineered cartilage images for quality control standardization

Osteoarthritis Cartilage. 2021 Jan 8;S1063-4584(21)00004-2. doi: 10.1016/j.joca.2020.12.018.Online ahead of print.

L Power 1L Acevedo 2R Yamashita 3D Rubin 4I Martin 5A Barbero 6


Cardiometabolic traits mediating the effect of education on osteoarthritis risk: a Mendelian randomization study

Osteoarthritis Cartilage. 2021 Jan 7;S1063-4584(21)00001-7. doi: 10.1016/j.joca.2020.12.015.Online ahead of print.

D Gill 1V Karhunen 2R Malik 3M Dichgans 4N Sofat 5


Scaffolds for Knee Chondral and Osteochondral Defects: Indications for Different Clinical Scenarios. A Consensus Statement

Cartilage. 2020 Jan 15;1947603519894729. doi: 10.1177/1947603519894729.Online ahead of print.

Giuseppe Filardo 1Luca Andriolo 2Peter Angele 3 4Massimo Berruto 5Mats Brittberg 6 7Vincenzo Condello 8Susan Chubinskaya 9Laura de Girolamo 10Alessandro Di Martino 2Berardo Di Matteo 11 12Justus Gille 13Alberto Gobbi 14Christian Lattermann 15Norimasa Nakamura 16Stefan Nehrer 17Giuseppe M Peretti 18 19Nogah Shabshin 20 21Peter Verdonk 22 23Kenneth Zaslav 24Elizaveta Kon 11 12 25


Spondyloarthritis evolution: what is in your history?

Curr Opin Rheumatol. 2020 Jul;32(4):321-329. doi: 10.1097/BOR.0000000000000712.

Maedeh Ashrafi 1Joerg Ermann 1 2Michael H Weisman 3


Bone Marrow Mesenchymal Stem Cell Therapy and Related Bone Marrow-Derived Orthobiologic Therapeutics

Curr Rev Musculoskelet Med. 2019 Dec;12(4):451-459.doi: 10.1007/s12178-019-09583-1.

Matthew T Kingery 1Amit K Manjunath 1Utkarsh Anil 1Eric J Strauss 2 3


The molecular profile of synovial fluid changes upon joint distraction and is associated with clinical response in knee osteoarthritis

Osteoarthritis Cartilage. 2020 Mar;28(3):324-333. doi: 10.1016/j.joca.2019.12.005.Epub 2020 Jan 2.

F E Watt 1B Hamid 2C Garriga 3A Judge 4R Hrusecka 5R J H Custers 6M P Jansen 7F P Lafeber 8S C Mastbergen 9T L Vincent 10


Stem cell-directed therapies for osteoarthritis: The promise and the practice

Stem Cells. 2020 Apr;38(4):477-486. doi: 10.1002/stem.3139. Epub 2020 Feb 7.

Jia Ng 1 2Christopher B Little 3 4Susan Woods 1 2Samuel Whittle 2Francis Y Lee 5Stan Gronthos 1 6Siddhartha Mukherjee 7David J Hunter 3Daniel L Worthley 1


Stepped Exercise Program for Patients With Knee Osteoarthritis : A Randomized Controlled Trial

Ann Intern Med. 2020 Dec 29. doi: 10.7326/M20-4447. Online ahead of print.

Kelli D Allen 1, Sandra Woolson 2, Helen M Hoenig 3, Dennis Bongiorni 2, James Byrd 4, Kevin Caves 5, Katherine S Hall 3, Bryan Heiderscheit 6, Nancy Jo Hodges 2, Kim M Huffman 3, Miriam C Morey 3, Shalini Ramasunder 3, Herbert Severson 7, Courtney Van Houtven 8, Lauren M Abbate 9, Cynthia J Coffman 10


Characterizing Pain and Generalized Sensory Sensitivity According to Trauma History Among Patients With Knee Osteoarthritis

Ann Behav Med. 2020 Dec 30;kaaa105. doi: 10.1093/abm/kaaa105. Online ahead of print.

Jennifer Pierce 1, Afton L Hassett 1, Chad M Brummett 1, Jenna McAfee 1, Christine Sieberg 2 3 4, Andrew Schrepf 1, Steven E Harte 1


Incidence and progression of ankle osteoarthritis: The johnston county osteoarthritis project

Semin Arthritis Rheum. 2020 Dec 21;51(1):230-235. doi: 10.1016/j.semarthrit.2020.10.015.Online ahead of print.

Ayesha Jaleel 1, Yvonne M Golightly 2, Carolina Alvarez 1, Jordan B Renner 3, Amanda E Nelson 4