Abstract Library

The summaries are free for public use. ARTHROS will continue to add and archive summaries of articles deemed relevant to ARTHROS by our Faculty.


Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity

ChemMedChem. 2022 Dec 30;e202200583. doi: 10.1002/cmdc.202200583.Online ahead of print.


Liridona Useini 1Marija Mojic 2Markus Laube 3Peter Lönnecke 1Sanja Mijatovic 2Danijela Maksimovic-Ivanic 2Jens Pietzsch 3 4Evamarie Hey-Hawkins 1


Gout Screening Identifies a Large Cardiovascular Population at Increased Risk of Mortality

J Clin Rheumatol. 2022 Dec 1;28(8):409-415. doi: 10.1097/RHU.0000000000001890.Epub 2022 Jul 30.


Silvia Ruiz-Simón 1Irene Calabuig 2Miguel Gómez-Garberí 3Mariano Andrés


Improved joint and patient-reported health assessments with pegloticase plus methotrexate co-therapy in patients with uncontrolled gout: 12-month exploratory outcomes of the MIRROR open-label trial

Arthritis Res Ther. 2022 Dec 27;24(1):281. doi: 10.1186/s13075-022-02979-4.


John K Botson 1Katie Obermeyer 2Brian LaMoreaux 2Lin Zhao 2Michael E Weinblatt 3Jeff Peterson 4


Factors associated with change in health-related quality of life in people with gout: a three-year prospective cohort study in primary care

Rheumatology (Oxford). 2022 Dec 21;keac706. doi: 10.1093/rheumatology/keac706.Online ahead of print.


Lorraine Watson 1John Belcher 1Elaine Nicholls 1 2Priyanka Chandratre 3Milica Blagojevic-Bucknall 1Samantha Hider 1 4Sarah A Lawton 1Christian D Mallen 1 4Sara Muller 1Keith Rome 5Edward Roddy 1 4


Interactions Between Genetic Risk and Diet Influencing Risk of Incident Female Gout: Discovery and Replication Analysis of Four Prospective Cohorts

Arthritis Rheumatol. 2022 Dec 13. doi: 10.1002/art.42419. Online ahead of print.


Kehuan Lin 1 2 3Natalie McCormick 2 3 4 5Chio Yokose 2 3 5Amit D Joshi 6Na Lu 4 6Gary C Curhan 6 7Tony R Merriman 8 9Kenneth G Saag 8Paul M Ridker 10Julie E Buring 1 10Daniel I Chasman 10Frank B Hu 1 6 11Hyon K Choi 2 3 4 5 6


Global burden of gout in 1990-2019: A systematic analysis of the Global Burden of Disease study 2019

Eur J Clin Invest. 2022 Dec 13;e13937. doi: 10.1111/eci.13937. Online ahead of print.


Yeon Jae Jeong 1Seoyeon Park 1Dong Keon Yon 2Seung Won Lee 3Kalthoum Tizaoui 4Ai Koyanagi 5 6 7Louis Jacob 5 8Karel Kostev 9Elena Dragioti 10Joaquim Radua 11 12 13 14Andrew Stickley 15Hans Oh 16Jae Il Shin 17Lee Smith 18


Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England

Rheumatology (Oxford). 2022 Nov 10;keac638. doi: 10.1093/rheumatology/keac638.Online ahead of print.


Mark D Russell 1Edward Roddy 2Andrew I Rutherford 3Benjamin Ellis 4Sam Norton 1Abdel Douiri 5Martin C Gulliford 5Andrew P Cope 1James B Galloway 1


Orthopaedic Management of Gout

J Am Acad Orthop Surg Glob Res Rev. 2022 Nov 8;6(11):e22.00216.doi: 10.5435/JAAOSGlobal-D-22-00216. eCollection 2022 Nov 1.


Anna R Cohen-Rosenblum 1Jason R SomogyiKelly K HynesMyriam E Guevara


Evaluating the association between food insecurity and risk of nephrolithiasis: an analysis of the National Health and Nutrition Examination Survey

World J Urol. 2022 Nov;40(11):2641-2647. doi: 10.1007/s00345-022-04150-9.Epub 2022 Sep 20.


Benjamin W Green 1Kevin Labagnara 1Eric Macdonald 1Nathan Feiertag 1Michael Zhu 1Kavita Gupta 1Charan Mohan 2Kara L Watts 1Arun Rai 2Alexander C Small 3


Development and Validation of an Emergency Department Electronic Medical Record Gout Flare Alert

Arthritis Care Res (Hoboken). 2022 Nov 21. doi: 10.1002/acr.25061. Online ahead of print.


Lesley E Jackson 1Narender Annapureddy 2Megan E Hansen 2Kenneth G Saag 1James Booth 3Giovanna Rosas 1Phillip J Foster 1Amy Mudano 1Dongmei Sun 1John D Osborne 4Tim Bongartz 5Erik Hess 5Colleen Lawrence 6Leah Dunkel 6Maria I Danila 1 7


Persistence with urate-lowering therapy in Australia: A longitudinal analysis of allopurinol prescriptions

Br J Clin Pharmacol. 2022 Nov;88(11):4894-4901. doi: 10.1111/bcp.15435. Epub 2022 Jun 21.


Matthew J Coleshill 1 2Richard O Day 1 2Karson Tam 1Mahsa Kouhkamari 3Vincent Caillet 3Eindra Aung 1 2Diluk R W Kannangara 1 4Peter Cronin 3Anthony Rodgers 5Sophie L Stocker 1 2 6


Anti-Inflammatory and Hypouricemic Effect of Bioactive Compounds: Molecular Evidence and Potential Application in the Management of Gout

Curr Issues Mol Biol. 2022 Oct 25;44(11):5173-5190. doi: 10.3390/cimb44110352.


Anna Scanu 1Roberto Luisetto 2Roberta Ramonda 1Paolo Spinella 3Paolo Sfriso 1Paola Galozzi 1Francesca Oliviero 1


Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial

Lancet. 2022 Oct 8;400(10359):1195-1205.doi: 10.1016/S0140-6736(22)01657-9.


Isla S Mackenzie 1Christopher J Hawkey 2Ian Ford 3Nicola Greenlaw 3Filippo Pigazzani 4Amy Rogers 4Allan D Struthers 4Alan G Begg 4Li Wei 5Anthony J Avery 6Jaspal S Taggar 6Andrew Walker 7Suzanne L Duce 4Rebecca J Barr 4Jennifer S Dumbleton 2Evelien D Rooke 4Jonathan N Townend 8Lewis D Ritchie 9Thomas M MacDonald 4ALL-HEART Study Group


  • ALL-HEART Study Group: 

Husnat AhmedPeter ArthurJane AzizLawrence BarnesSarah BoyleTom BrightonMorris BrownMark CaulfieldJesse DawsonMartin DenvirAlexander Sf DoneySagar DoshiMoira DryburghMichael EddlestonJim FinlaysonAhmet FuatJacqueline FurnaceJw Kerr GrieveGreg GuthrieSharon HamEmma IsaardClaudine JenningsRichard JohnsonClaire KerrSohail KhanKailash KrishnanSusan LongAnne MackintoshMary Joan MacleodTerry McCormackPaul McElenyMonique MorarAdnan NadirDavid NewbyColin PetrieDavid PreissStuart RalstonMarc RandallHelen RoutledgeSaad ShakirRaj SharmaBridget ShepherdDon SimsGordon SneddenJasper TrevelyanChristopher WeirRobin WeirKirsty WetherallRobbie WilsonAdam WilsonKris Zutis


Monosodium urate deposition in the lumbosacral spine of patients with gout compared with non-gout controls: A dual-energy CT study

Semin Arthritis Rheum. 2022 Oct;56:152064. doi: 10.1016/j.semarthrit.2022.152064.Epub 2022 Jun 30.


Michael Toprover 1Michael Mechlin 2Theodore Fields 3Cheongeun Oh 4Fabio Becce 5Michael H Pillinger 6


Onset of depression and anxiety among patients with gout after diagnosis: a population-based incident cohort study

BMC Rheumatol. 2022 Oct 3;6(1):56. doi: 10.1186/s41927-022-00288-6.


Alyssa Howren 1 2 3Eric C Sayre 3Hyon K Choi 3 4J Antonio Avina-Zubieta 3 5Kam Shojania 3 5 6Jamie Y Park 1 2 3Mary A De Vera 7 8 9 10


Predictors of Patient and Physician Assessments of Gout Control

Arthritis Care Res (Hoboken). 2022 Oct 20. doi: 10.1002/acr.25046. Online ahead of print.


Nicola Dalbeth 1Christopher Frampton 2Maple Fung 3Scott Baumgartner 3Hyon K Choi 4


Nationwide racial/ethnic disparities in US emergency department visits and hospitalizations for gout

Rheumatology (Oxford). 2022 Oct 11;keac590. doi: 10.1093/rheumatology/keac590.Online ahead of print.


Chio Yokose 1 2Natalie McCormick 1 2 3Na Lu 3 4Amit D Joshi 4Lesley Jackson 5Minna J Kohler 1Janeth Yinh 1Yuqing Zhang 1 2John Hsu 6 7Nicola Dalbeth 8Kenneth G Saag 5Hyon K Choi 1 2


Effect modification by contextual factors of urate-lowering therapy on serum urate in people with gout: A systematic review with meta-regression analysis

Semin Arthritis Rheum. 2022 Oct;56:152049.doi: 10.1016/j.semarthrit.2022.152049. Epub 2022 Jun 15.


Ritch Te Kampe 1Sabrina Mai Nielsen 2Ioana Hotea 3Caroline van Durme 4Robin Christensen 2Annelies Boonen 5


The clinician's guide to prevention and treatment of osteoporosis

Osteoporos Int. 2022 Oct;33(10):2049-2102. doi: 10.1007/s00198-021-05900-y.Epub 2022 Apr 28.


M S LeBoff 1S L Greenspan 2K L Insogna 3E M Lewiecki 4K G Saag 5A J Singer 6E S Siris 7


Community Practice Experiences with a Variety of Immunomodulatory Agents Co-Administered with Pegloticase for the Treatment of Uncontrolled Gout

Rheumatol Ther. 2022 Dec;9(6):1549-1558. doi: 10.1007/s40744-022-00492-3.Epub 2022 Sep 22.


Aaron Broadwell 1John A Albert 2Lissa Padnick-Silver 3Brian LaMoreaux 4


Change in serum urate level with urate-lowering therapy initiation associates in the immediate term with patient-reported outcomes in people with gout

Semin Arthritis Rheum. 2022 Oct;56:152057. doi: 10.1016/j.semarthrit.2022.152057.Epub 2022 Jun 29.


Ruth Topless 1Siamak Noorbaloochi 2Tony R Merriman 3Jasvinder A Singh 4


A Randomized Placebo-Controlled Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled GOut Receiving Pegloticase (MIRROR RCT): Primary Efficacy and Safety Findings

Arthritis Rheumatol. 2022 Sep 13. doi: 10.1002/art.42335. Online ahead of print.


John K Botson 1Kenneth Saag 2Jeff Peterson 3Naval Parikh 4Stephen Ong 5Dan La 6Karon LoCicero 7Katie Obermeyer 8Yan Xin 8Jason Chamberlain 8Brian LaMoreaux 8Supra Verma 8Stephen Sainati 8Suneet Grewal 9Amar Majjhoo 10John R P Tesser 11Michael E Weinblatt 12


In patients with acute mono-oligoarthritis, a targeted ultrasound scanning protocol shows great accuracy for the diagnosis of gout and CPPD

Rheumatology (Oxford). 2022 Aug 23;keac479. doi: 10.1093/rheumatology/keac479.Online ahead of print.


Edoardo Cipolletta 1 2Emilio Filippucci 1Abhishek Abhishek 2Jacopo Di Battista 1Gianluca Smerilli 1Marco Di Carlo 1Ferdinando Silveri 1Rossella De Angelis 1Fausto Salaffi 1Walter Grassi 1Andrea Di Matteo 1


Critical appraisal of serum urate targets in the management of gout

Nat Rev Rheumatol. 2022 Aug 16. doi: 10.1038/s41584-022-00816-1.Online ahead of print.


Lisa K Stamp 1Nicola Dalbeth 2


Predictors of disease activity in gout: a 12-month analysis of the ATTACk (Achieving improvement in the management of crystal-induced arthritis) multicentre cohort study

Clin Exp Rheumatol. 2022 Aug 5. doi: 10.55563/clinexprheumatol/eh0jcp. Online ahead of print.


Mariagrazia Lorenzin 1Nicola Ughi 2Alarico Ariani 3Bernd Raffeiner 4Paola Frallonardo 5Ariela Hoxha 6Augusta Ortolan 1Marta Favero 7Simone Parisi 8Alessandra Bortoluzzi 9Fulvia Ceccarelli 10Ramona Lucchetti 10Federica Furini 9Teresa Del Ross 1Anna Zanetti 11Greta Carrara 12Carlo Alberto Scirè 13Andrea Doria 1Roberta Ramonda 14SIR Study Group ATTACk



  • SIR Study Group ATTACk: 

Fausto SalaffiAndrea Di MatteoEnrico FusaroMarcello GovoniMaria ManaraAntonella MurgoLaura RotunnoMarco Amadeo Cimmino


A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, immunogenicity, and pharmacokinetic findings during long-term extension of an open-label study

Arthritis Res Ther. 2022 Aug 25;24(1):208.doi: 10.1186/s13075-022-02865-z.


John K Botson 1John R P Tesser 2Ralph Bennett 2Howard M Kenney 3Paul M Peloso 4Katie Obermeyer 4Yang Song 5Brian LaMoreaux 4Lin Zhao 4Yan Xin 5Jason Chamberlain 5Srini Ramanathan 5Michael E Weinblatt 6Jeff Peterson 7


Characteristics and Outcomes of People With Gout Hospitalized Due to COVID-19: Data From the COVID-19 Global Rheumatology Alliance Physician-Reported Registry

ACR Open Rheumatol. 2022 Aug 24. doi: 10.1002/acr2.11495. Online ahead of print.


Kanon Jatuworapruk 1Anna Montgomery 2Milena Gianfrancesco 2Richard Conway 3Laura Durcan 4Elizabeth R Graef 5Aruni Jayatilleke 6Helen Keen 7Adam Kilian 8Kristen Young 9Loreto Carmona 10Adriana Karina Cogo 11Alí Duarte-García 12Laure Gossec 13Rebecca Hasseli 14Kimme L Hyrich 15Vincent Langlois 16Saskia Lawson-Tovey 17Armando Malcata 18Elsa F Mateus 19Martin Schafer 20Carlo Alberto Scirè 21Valgerdur Sigurdardottir 22Jeffrey A Sparks 23Anja Strangfeld 20Ricardo M Xavier 24Suleman Bhana 25Monique Gore-Massy 26Jonathan Hausmann 27Jean W Liew 5Emily Sirotich 28Paul Sufka 29Zach Wallace 30Pedro M Machado 31Jinoos Yazdany 2Rebecca Grainger 32Philip C Robinson 33


Effects of vitamin C supplementation on gout risk: results from the Physicians' Health Study II trial

Am J Clin Nutr. 2022 Sep 2;116(3):812-819.doi: 10.1093/ajcn/nqac140.


Stephen P Juraschek 1J Michael Gaziano 2 3Robert J Glynn 4 5Natalya Gomelskaya 4Vadim Y Bubes 4Julie E Buring 4 6Robert H Shmerling 7Howard D Sesso 2 4 6


Treatment Guidelines in Gout

Rheum Dis Clin North Am. 2022 Aug;48(3):659-678. doi: 10.1016/j.rdc.2022.04.003.


Allan C Gelber 1


A glance into the future of gout

Ther Adv Musculoskelet Dis. 2022 Jul 28;14:1759720X221114098.doi: 10.1177/1759720X221114098. eCollection 2022.


Francisca Sivera 1Mariano Andres 2Nicola Dalbeth 3


Evaluation of the Relationship Between Serum Urate Levels, Clinical Manifestations of Gout, and Death From Cardiovascular Causes in Patients Receiving Febuxostat or Allopurinol in an Outcomes Trial

Arthritis Rheumatol. 2022 Sep;74(9):1593-1601.doi: 10.1002/art.42160. Epub 2022 Aug 5.


Kenneth G Saag 1Michael A Becker 2William B White 3Andrew Whelton 4Jeffrey S Borer 5Philip B Gorelick 6Barbara Hunt 7Majin Castillo 7Lhanoo Gunawardhana 7CARES Investigators


CARES Investigators: 

Eric LloydSimon WigfieldLauren GwynneDanielle Johnson


Moving the Needle in Gout Management: The Role of Culture, Diet, Genetics, and Personalized Patient Care Practices

Nutrients. 2022 Aug 31;14(17):3590. doi: 10.3390/nu14173590.


Youssef M Roman 1


Management of gout following 2016/2017 European (EULAR) and British (BSR) guidelines: An interrupted time-series analysis in the United Kingdom

Lancet Reg Health Eur. 2022 May 25;18:100416. doi: 10.1016/j.lanepe.2022.100416.eCollection 2022 Jul.


Mark D Russell 1Andrew I Rutherford 2Benjamin Ellis 3Sam Norton 1Abdel Douiri 4Martin C Gulliford 4Andrew P Cope 1James B Galloway 1


Population pharmacokinetic modelling of febuxostat in healthy subjects and people with gout

Br J Clin Pharmacol. 2022 Jul 18. doi: 10.1111/bcp.15462. Online ahead of print.


Bishoy Kamel 1 2 3 4Ahmad Y Abuhelwa 5 6 7David Foster 7Janna K Duong 8Garry G Graham 3 4Kenneth M Williams 3 4Kevin D Pile 9 10Richard O Day 2 3


Dual Energy CT Has Additional Prognostic Value over Clinical Measures in Gout Including Tophi: A Systematic Literature Review

J Rheumatol. 2022 Jul 15;jrheum.211246. doi: 10.3899/jrheum.211246. Online ahead of print.


Sally K Stauder 1Paul M Peloso 1


Long-term follow-up of a randomised controlled trial of allopurinol dose escalation to achieve target serum urate in people with gout

J Rheumatol. 2022 Jul 1;jrheum.220270. doi: 10.3899/jrheum.220270. Online ahead of print.


George B Coleman 1Nicola Dalbeth 1Chris Frampton 1Janine Haslett 1Jill Drake 1Isabel Su 1Anne M Horne 1Lisa K Stamp 1


Emerging strategies for treating gout

Curr Opin Pharmacol. 2022 May 19;65:102241. doi: 10.1016/j.coph.2022.102241.Online ahead of print.


Edward M Huddleston 1Angelo L Gaffo 2


Pharmacist knowledge of gout management: impact of an educational intervention

BMC Rheumatol. 2022 May 23;6(1):30. doi: 10.1186/s41927-022-00259-x.


Emma R Dorris 1Mariosa Kieran 2Nicola Dalbeth 3Geraldine McCarthy 4 5


Gout and Hospital Admission for Ambulatory Care-Sensitive Conditions: Risks and Trajectories

J Rheumatol. 2022 Jul;49(7):731-739. doi: 10.3899/jrheum.220038. Epub 2022 Apr 15.


Ali Kiadaliri 1Tuhina Neogi 2Martin Englund 3


Gout increases length of stay in patients hospitalized for heart failure exacerbation

Ther Adv Musculoskelet Dis. 2022 Jun 14;14:1759720X221102853.doi: 10.1177/1759720X221102853. eCollection 2022.


Daniel DeMizio 1Guojing Wu 2Ying Wei 2Joan Bathon 3Runsheng Wang 1


Risk of gout flares after COVID-19 vaccination: A case-crossover study

Semin Arthritis Rheum. 2022 Jun 28;56:152059. doi: 10.1016/j.semarthrit.2022.152059.Online ahead of print.


Hui Li 1Nicola Dalbeth 2Zachary S Wallace 3Jeffrey A Sparks 4Xiaoxiao Li 5Chao Zeng 6Yilun Wang 1Dongxing Xie 1Guanghua Lei 6Jie Wei 7Yuqing Zhang 8


Development and usability of a web-based patient-tailored tool to support adherence to urate-lowering therapy in gout

BMC Med Inform Decis Mak. 2022 Apr 7;22(1):95. doi: 10.1186/s12911-022-01833-6.


Ritch Te Kampe 1 2 3Annelies Boonen 4 5Tim L Jansen 6Jan Mathis Elling 5 7Marcel Flendrie 8Yvonne van Eijk-Hustings 9Matthijs Janssen 6Caroline van Durme 4 10Hein de Vries 5 7


Professionals' perspectives on existing practice and conditions for nurse-led gout care based on treatment recommendations: a qualitative study in primary healthcare

BMC Prim Care. 2022 Apr 7;23(1):71. doi: 10.1186/s12875-022-01677-z.


Helene Sedelius 1 2Malin Tistad 3 4Ulrika Bergsten 5Mats Dehlin 6David Iggman 7Lars Wallin 3Anna Svärd 7


Incident Gout: Risk of Death and Cause-Specific Mortality in Western Sweden: A Prospective, Controlled Inception Cohort Study

Front Med (Lausanne). 2022 Feb 24;9:802856. doi: 10.3389/fmed.2022.802856.eCollection 2022.


Mats Dehlin 1Tatiana Zverkova Sandström 1Lennart Th Jacobsson 1


Treating gout - can hypouricemia produced by moderate doses of combined oral treatment give early treatment success? Preliminary observations

Nucleosides Nucleotides Nucleic Acids. 2022 Mar 8;1-12. doi: 10.1080/15257770.2022.2039394.Online ahead of print.


Werner Löffler 1Lynette Fairbanks 2Terry Gibson 3


Association of colchicine use for acute gout with clinical outcomes in acute decompensated heart failure

Clin Cardiol. 2022 Apr 28. doi: 10.1002/clc.23830. Online ahead of print.


Mary E Roth 1Melissa E Chinn 1Steven P Dunn 1Kenneth C Bilchick 2Sula Mazimba 2


Enhancing the Response Rate to Recombinant Uricases in Patients with Gout

BioDrugs. 2022 Mar;36(2):95-103. doi: 10.1007/s40259-022-00517-x.Epub 2022 Mar 22.


Naomi Schlesinger 1Lissa Padnick-Silver 2Brian LaMoreaux 3


Update on gout management: what is old and what is new

Curr Opin Rheumatol. 2022 Mar 1;34(2):118-124.doi: 10.1097/BOR.0000000000000861.


Yuliya Afinogenova 1Abhijeet Danve 1Tuhina Neogi 2


Managing Cardiovascular Risk in Patients with Rheumatic Disease

Rheum Dis Clin North Am. 2022 May;48(2):429-444. doi: 10.1016/j.rdc.2022.02.003.

Lyn D Ferguson 1Naveed Sattar 2Iain B McInnes 3


Management and Cure of Gouty Arthritis

Rheum Dis Clin North Am. 2022 May;48(2):479-492. doi: 10.1016/j.rdc.2022.03.001.


Sarah F Keller 1Brian F Mandell 2


Gout management and outcomes during established COVID-19 pandemic in 2020-2021: a cross-sectional Internet survey

Ther Adv Musculoskelet Dis. 2022 May 13;14:1759720X221096381.doi: 10.1177/1759720X221096381. eCollection 2022.


Jasvinder A Singh 1N Lawrence Edwards 2


Effects of intensive urate lowering therapy with febuxostat in comparison with allopurinol on pulse wave velocity in patients with gout and increased cardiovascular risk: the FORWARD study

Eur Heart J Cardiovasc Pharmacother. 2022 May 5;8(3):236-242.doi: 10.1093/ehjcvp/pvaa144.


Giovambattista Desideri 1Marek Rajzer 2Martijn Gerritsen 3Michael T Nurmohamed 4Cristina Giannattasio 5Anne-Kathrin Tausche 6Claudio Borghi 7


Update of the current role of ultrasound in asymptomatic hyperuricemia. A systematic literature review

Joint Bone Spine. 2022 May;89(3):105335. doi: 10.1016/j.jbspin.2021.105335. Epub 2021 Dec 22.


Marwin Gutierrez 1Hugo Sandoval 2Chiara Bertolazzi 3Carina Soto-Fajardo 3Rene Martin Tellez-Gastelum 4Anthony M Reginato 5Denise Clavijo-Cornejo 6


Erectile dysfunction in hyperuricemia: A prevalence meta-analysis and meta-regression study

Andrology. 2022 Jan;10(1):72-81. doi: 10.1111/andr.13088. Epub 2021 Aug 16.


Maria Totaro 1Sotirios Dimarakis 1Chiara Castellini 1Settimio D'Andrea 1Antonio Parisi 1Federica D'Amato 1Daniele Tienforti 1Sara Palazzi 1Marco Giorgio Baroni 2Sandro Francavilla 1Arcangelo Barbonetti 1


Clinical interventions to improve adherence to urate-lowering therapy in patients with gout: a systematic review

Int J Pharm Pract. 2022 Apr 13;riac025. doi: 10.1093/ijpp/riac025. Online ahead of print.


Klarissa A Sinnappah 1Sophie L Stocker 2 3 4Jian Sheng Chan 3 4Dyfrig A Hughes 5Daniel F B Wright 1


Empagliflozin and uric acid metabolism in diabetes: A post hoc analysis of the EMPA-REG OUTCOME trial

Diabetes Obes Metab. 2022 Jan;24(1):135-141.doi: 10.1111/dom.14559. Epub 2021 Oct 4.


João Pedro Ferreira 1 2Silvio E Inzucchi 3Michaela Mattheus 4Thomas Meinicke 4Dominik Steubl 4 5Christoph Wanner 6Bernard Zinman 7


Treatment advances in gout

Best Pract Res Clin Rheumatol. 2021 Dec;35(4):101719.doi: 10.1016/j.berh.2021.101719. Epub 2021 Oct 28.


Lisa K Stamp 1Hamish Farquhar 2


Managing Gout in Women: Current Perspectives

J Inflamm Res. 2022 Mar 3;15:1591-1598. doi: 10.2147/JIR.S284759.eCollection 2022.


Aakash V Patel 1Angelo L Gaffo 2 3


Elevated Serum Uric Acid and Cardiovascular Disease: A Review and Potential Therapeutic Interventions

Cureus. 2022 Mar 28;14(3):e23582. doi: 10.7759/cureus.23582.eCollection 2022 Mar.


Michael Freilich 1Andrew Arredondo 1Seyedeh Leila Zonnoor 1Isabel M McFarlane 1


Gout and the COVID-19 pandemic

Curr Opin Rheumatol. 2022 Mar 1;34(2):111-117.doi: 10.1097/BOR.0000000000000860.


Vicky Tai 1Philip C Robinson 2 3Nicola Dalbeth 1


Improvement in hepatic fibrosis estimated by Fibrosis-4 index in pegloticase treated chronic refractory gout patients

Clin Exp Rheumatol. 2022 Mar 23. doi: 10.55563/clinexprheumatol/1138gr. Online ahead of print.

Naomi Schlesinger 1Vinod K Rustgi 2Anthony E Yeo 3Peter E Lipsky 4


The challenge of gout flare measurement

Best Pract Res Clin Rheumatol. 2021 Dec;35(4):101716.doi: 10.1016/j.berh.2021.101716. Epub 2021 Oct 9.

Sarah Stewart 1Nicola Dalbeth 2Angelo Gaffo 3


Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management

NEJM Evid. 2022 Mar;1(3):10.1056/evidoa2100028. doi: 10.1056/evidoa2100028.Epub 2022 Feb 3.

James R O'Dell 1 2Mary T Brophy 3 4Michael H Pillinger 5 6Tuhina Neogi 7Paul M Palevsky 8 9Hongsheng Wu 3 10Anne Davis-Karim 11Jeff A Newcomb 1 2Ryan Ferguson 3David Pittman 11Grant W Cannon 12Thomas Taylor 13 14Robert Terkeltaub 15Amy C Cannella 1 2Bryant R England 1 2Lindsay N Helget 1 2Ted R Mikuls 1 2


Gout As a Predictor of Total Knee Arthroplasty Outcomes and Costs

J Knee Surg. 2022 Mar;35(4):362-366. doi: 10.1055/s-0040-1715098. Epub 2020 Aug 24.

Samuel Rosas # 1Andrey Zuskov # 1Tianyi David Luo 1Martin W Roche 2Cynthia L Emory 1Johannes F Plate 1


Consensus Statement Regarding the Efficacy and Safety of Long-Term Low-Dose Colchicine in Gout and Cardiovascular Disease

Am J Med. 2022 Jan;135(1):32-38. doi: 10.1016/j.amjmed.2021.07.025.Epub 2021 Aug 18.

Philip C Robinson 1Robert Terkeltaub 2Michael H Pillinger 3Binita Shah 4Vangelis Karalis 5Eleni Karatza 5David Liew 6Massimo Imazio 7Jan H Cornel 8Peter L Thompson 9Mark Nidorf 10


Does seasonality of the microbiota contribute to the seasonality of acute gout flare?

Clin Exp Rheumatol. 2022 Mar 30. doi: 10.55563/clinexprheumatol/hdtge7.Online ahead of print.

Naomi Schlesinger 1Luigi Brunetti 2Ioannis P Androulakis 3


Randomised controlled trial targeting habit formation to improve medication adherence to daily oral medications in patients with gout

BMJ Open. 2021 Nov 24;11(11):e055930.doi: 10.1136/bmjopen-2021-055930.

Constance P Fontanet 1 2Niteesh K Choudhry 1 2Wendy Wood 3Ted Robertson 4Nancy Haff 1 2Rebecca Oran 4Ellen S Sears 1 2Erin Kim 1 2Kaitlin Hanken 1 2Renee A Barlev 1 2Julie C Lauffenburger 1Candace H Feldman 5 6


Temporal Trends in COVID-19 outcomes in People with Rheumatic Diseases in Ireland: data from the COVID-19 Global Rheumatology Alliance registry

Rheumatology (Oxford). 2022 Mar 8;keac142. doi: 10.1093/rheumatology/keac142.Online ahead of print.

Richard Conway 1 2Elena Nikiphorou 3 4Christiana A Demetriou 5Candice Low 6Kelly Leamy 7John G Ryan 8Ronan Kavanagh 9Alexander D Fraser 10 11John J Carey 12 13Paul O'Connell 14 15Rachael M Flood 2 16Ronan H Mullan 2 16David J Kane 2 16Nicola Ambrose 17Frances Stafford 17Philip C Robinson 18Jean W Liew 19Rebecca Grainger 20Geraldine M McCarthy 7COVID-19 Global Rheumatology Alliance


What's new on the front-line of gout pharmacotherapy?

Expert Opin Pharmacother. 2022 Mar;23(4):453-464.doi: 10.1080/14656566.2021.2020249. Epub 2022 Jan 5.

Kurt E G Blake 1, Jordan L Saag 2, Kenneth G Saag 3


Expert Opinion on Pegloticase with Concomitant Immunomodulatory Therapy in the Treatment of Uncontrolled Gout to Improve Efficacy, Safety, and Durability of Response

Curr Rheumatol Rep. 2022 Jan;24(1):12-19. doi: 10.1007/s11926-022-01055-9.Epub 2022 Feb 15.

John K Botson 1, Herbert S B Baraf 2, Robert T Keenan 3, John Albert 4, Karim R Masri 5, Jeff Peterson 6, Christianne Yung 7, Brigid Freyne 8, Mona Amin 9, Abdul Abdellatif 10, Nehad Soloman 11, N Lawrence Edwards 12, Vibeke Strand 13


U-shaped association of uric acid to overall-cause mortality and its impact on clinical management of hyperuricemia

Redox Biol. 2022 Feb 17;51:102271. doi: 10.1016/j.redox.2022.102271.Online ahead of print.

William T Crawley 1, Cyprien G Jungels 1, Kurt R Stenmark 2, Mehdi A Fini 3


Racial Disparities in the Modern Gout Epidemic

J Rheumatol. 2022 Mar 15;jrheum.220173. doi: 10.3899/jrheum.220173.Online ahead of print.

Natalie McCormick 1, Hyon K Choi 1


Cause-Specific Mortality in Patients with Gout in the United States Veteran's Health Administration: A Matched Cohort Study

Arthritis Care Res (Hoboken). 2022 Mar 16. doi: 10.1002/acr.24881. Online ahead of print.

Lindsay N Helget 1 2, Bryant R England 1 2, Punyasha Roul 1 2, Harlan Sayles 2 3, Alison D Petro 1 2, Tuhina Neogi 4, James R O'Dell 1 2, Ted R Mikuls 1 2


Hospitalizations for acute gout: process mapping the inpatient journey and identifying predictors of admission

J Rheumatol. 2022 Mar 15;jrheum.211203. doi: 10.3899/jrheum.211203. Online ahead of print.

Mark D Russell 1, Deepak Nagra 1, Benjamin D Clarke 1, Sathiyaa Balachandran 1, April Buazon 1, Amy Boalch 1, Katie Bechman 1, Maryam A Adas 1, Edward G Alveyn 1, Andrew I Rutherford 1, James B Galloway 1


Disease modification in gout: a qualitative study of gout expert rheumatologists

Rheumatol Adv Pract. 2022 Jan 3;6(1):rkab107. doi: 10.1093/rap/rkab107. eCollection 2022.

Jasvinder A Singh 1 2


Gout gone awry: The importance of proper diagnosis

Clin Case Rep. 2021 Dec 16;9(12):e05201. doi: 10.1002/ccr3.5201. eCollection 2021 Dec.

Sophia Tessema 1, Abdullahi E Mahgoub 2, Rasha Nakhleh 3


The relationship between metabolic syndrome severity and the risk of mortality in gout patients: a population-based study

Clin Exp Rheumatol. 2022 Feb 1. Online ahead of print.

Naomi Schlesinger 1, Mohamed I Elsaid 2, Vinod K Rustgi 3


Pegloticase causes prolonged improvement in multiple disease parameters in patients with chronic refractory gout who maintain low serum urate levels

Clin Exp Rheumatol. 2022 Feb 25. Online ahead of print.

Robert T Keenan 1, Anthony E Yeo 2, Peter E Lipsky 3


Gout Arthritis During Admission for Decompensated Heart Failure-A Descriptive Analysis of Risk Factors, Treatment and Prognosis

Front Med (Lausanne). 2022 Feb 14;9:789414. doi: 10.3389/fmed.2022.789414.eCollection 2022.

Fabian Ritter 1, Fabian Franzeck 2, Julian Geisshardt 1, Ulrich A Walker 3, Michael Osthoff 1 4


A systematic review of the drug-drug interaction between statins and colchicine: Patient characteristics, etiologies, and clinical management strategies

Pharmacotherapy. 2022 Feb 17. doi: 10.1002/phar.2674. Online ahead of print.

Nicholas C Schwier 1, Cyrille K Cornelio 2, Paul M Boylan 1


Why do patients with gout not take allopurinol?

J Rheumatol. 2022 Feb 15;jrheum.210950. doi: 10.3899/jrheum.210950. Online ahead of print.

Yasaman Emad 1, Nicola Dalbeth 1, John Weinman 1, Trudie Chalder 1, Keith J Petrie 1


Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study

Lancet Rheumatol. 2022 Jan 28. doi: 10.1016/S2665-9913(21)00401-X. Online ahead of print.

Ruth K Topless 1, Angelo Gaffo 2 3, Lisa K Stamp 4, Philip C Robinson 5, Nicola Dalbeth 6, Tony R Merriman 1 2


Modifiable Factors and Incident Gout across Ethnicity within a Large Multiethnic Cohort of Older Adults

J Rheumatol. 2022 Feb 1;jrheum.210394. doi: 10.3899/jrheum.210394. Online ahead of print.

Mika D Thompson 1, Yan Yan Wu 1, Robert V Cooney 1, Lynne R Wilkens 1, Christopher A Haiman 1, Catherine M Pirkle 1


Is repeat serum urate testing superior to a single test to predict incident gout over time?

PLoS One. 2022 Feb 1;17(2):e0263175. doi: 10.1371/journal.pone.0263175. eCollection 2022.

Sarah Stewart 1, Amanda Phipps-Green 2, Greg D Gamble 1, Lisa K Stamp 3, William J Taylor 4, Tuhina Neogi 5, Tony R Merriman 2, Nicola Dalbeth 1


The Relation of Accelerometer-Measured Physical Activity and Serum Uric Acid Using the National Health and Nutrition Survey (NHANES) 2003-2004

Front Sports Act Living. 2022 Jan 12;3:775398. doi: 10.3389/fspor.2021.775398.eCollection 2021.

Isaac D Smith 1 2, Leanna M Ross 1 3, Josi R Gabaldon 3 4, Nicholas Holdgate 5, Carl F Pieper 6, Tony C Ning 7, William E Kraus 1 3 8, Kim M Huffman 1 2 3


Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging

J Clin Med. 2021 Dec 29;11(1):166. doi: 10.3390/jcm11010166.

Jennifer S Weaver 1, Ernest R Vina 2, Peter L Munk 3 4, Andrea S Klauser 5, Jamie M Elifritz 6 7, Mihra S Taljanovic 1 8


Gout Flare Severity From the Patient Perspective: A Qualitative Interview Study

Arthritis Care Res (Hoboken). 2022 Feb;74(2):317-323. doi: 10.1002/acr.24475.Epub 2022 Jan 8.

Andrea Garcia-Guillen 1Sarah Stewart 2Isabel Su 2William J Taylor 3Angelo L Gaffo 4Merryn Gott 2Julia Slark 2Anne Horne 2Nicola Dalbeth 2


Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series

J Clin Rheumatol. 2022 Jan 1;28(1):e129-e134.doi: 10.1097/RHU.0000000000001639.

John K Botson 1Jeff Peterson 2


Mortality in Patients With Gout Treated With Allopurinol: A Systematic Review and Meta-Analysis

Arthritis Care Res (Hoboken). 2021 Jul;73(7):1049-1054.doi: 10.1002/acr.24205. Epub 2021 Jun 18.

Charles A Hay 1James A Prior 1John Belcher 1Christian D Mallen 1Edward Roddy 1


Effectiveness of Allopurinol in Reducing Mortality: Time-Related Biases in Observational Studies

Arthritis Rheumatol. 2021 Sep;73(9):1749-1757. doi: 10.1002/art.41710.Epub 2021 Jul 27.

Samy Suissa 1Karine Suissa 2Marie Hudson 1


Consensus-based semi-quantitative ultrasound scoring system for gout lesions: Results of an OMERACT Delphi process and web-reliability exercise

Semin Arthritis Rheum. 2021 Jun;51(3):644-649. doi: 10.1016/j.semarthrit.2020.11.011.Epub 2021 Jan 10.

Sara Nysom Christiansen 1Georgios Filippou 2Carlo Alberto Scirè 3Peter V Balint 4George Aw Bruyn 5Nicola Dalbeth 6Christian Dejaco 7Andrea Delle Sedie 8Emilio Filippucci 9Hilde B Hammer 10Annamaria Iagnocco 11Helen I Keen 12Eugene Y Kissin 13Juhani Koski 14Peter Mandl 15Julia Martin 6Eugenio De Miguel 16Ingrid Möller 17Esperanza Naredo 18Carlos Pineda 19Wolfgang A Schmidt 20Sarah Stewart 6Maria Antonietta D'Agostino 21Lene Terslev 22on the behalf of the OMERACT Ultrasound working group


Hyperuricaemia, gout and allopurinol in the CKD Queensland registry

J Nephrol. 2021 Jun;34(3):753-762. doi: 10.1007/s40620-020-00937-4. Epub 2021 Jan 13.

A Jeyaruban 1 2 3W Hoy 4 5A Cameron 4 5H Healy 4 5 6Z Wang 4 5J Zhang 4 5A Mallett 4 5 6


Efficacy and Tolerability of Miltefosine in the Treatment of Cutaneous Leishmaniasis

Clin Infect Dis. 2021 Oct 5;73(7):e2457-e2562. doi: 10.1093/cid/ciaa1238.

JeanAnne M Ware 1Elise M O'Connell 1Thomas Brown 1Lauren Wetzler 1Kawsar R Talaat 2Thomas B Nutman 1Theodore E Nash 1


Serious Infections in Patients With Gout in the US: A National Study of Incidence, Time Trends, and Outcomes

Arthritis Care Res (Hoboken). 2021 Jun;73(6):898-908. doi: 10.1002/acr.24201.

Jasvinder A Singh 1John D Cleveland 2


Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) common language definition of gout

RMD Open. 2021 Apr;7(2):e001623. doi: 10.1136/rmdopen-2021-001623.

Rachel Murdoch 1Michael J Barry 2Hyon K Choi 3Daniel Hernandez 4Brianne Johnsen 3Manuel Labrador 5Susan Reid 1Jasvinder A Singh 6 7Robert Terkeltaub 8Janitzia Vázquez Mellado 5Nicola Dalbeth 9


How to Differentiate Gout, Calcium Pyrophosphate Deposition Disease, and Osteoarthritis Using Just Four Clinical Parameters

Diagnostics (Basel). 2021 May 21;11(6):924. doi: 10.3390/diagnostics11060924.

Dmitrij Kravchenko 1Raoul Bergner 2Charlotte Behning 3Valentin Sebastian Schäfer 4


Different Food Sources of Fructose-Containing Sugars and Fasting Blood Uric Acid Levels: A Systematic Review and Meta-Analysis of Controlled Feeding Trials

J Nutr. 2021 Aug 7;151(8):2409-2421. doi: 10.1093/jn/nxab144.

Sabrina Ayoub-Charette 1 2Laura Chiavaroli 1 2Qi Liu 1 2Tauseef Ahmad Khan 1 2Andreea Zurbau 1 2 3Fei Au-Yeung 1 2 3Annette Cheung 1 2Amna Ahmed 1 2Danielle Lee 1 2Vivian L Choo 1 2 4Sonia Blanco Mejia 1 2Russell J de Souza 1 2 5 6Thomas Ms Wolever 1 2 3 7 8Lawrence A Leiter 1 2 7 8 9Cyril Wc Kendall 1 2 10David Ja Jenkins 1 2 7 8 9John L Sievenpiper 1 2 7 8 9


COVID-19 in patients with gout on colchicine

Rheumatol Int. 2021 Aug;41(8):1503-1507. doi: 10.1007/s00296-021-04902-7.Epub 2021 Jun 5.

Eleftherios Pelechas 1Vassiliki Drossou 1Paraskevi V Voulgari 1Alexandros A Drosos 2


Allopurinol hepatotoxicity is associated with human leukocyte antigen Class I alleles

Liver Int. 2021 Aug;41(8):1884-1893. doi: 10.1111/liv.14903. Epub 2021 May 7.

Robert J Fontana 1Yi-Ju Li 2Elizabeth Phillips 3Naba Saeed 4Huiman Barnhart 2David Kleiner 5Jay Hoofnagle 6Drug Induced Liver Injury Network


A patient-centered gout information value chain: a scoping review

Patient Educ Couns. 2021 Jun 8;S0738-3991(21)00405-5.doi: 10.1016/j.pec.2021.06.007. Online ahead of print.

Maranda J Russell 1Sujin Kim 2Aleksander Lenert 3


Global patterns of treat-to-serum urate target care for gout: Systematic review and meta-analysis

Semin Arthritis Rheum. 2021 Apr 25;51(4):677-684. doi: 10.1016/j.semarthrit.2021.04.011.Online ahead of print.

Chang-Nam Son 1Sarah Stewart 2Isabel Su 2Borislav Mihov 2Gregory Gamble 2Nicola Dalbeth 3


Cardiovascular Safety of Febuxostat and Allopurinol in Hyperuricemic Patients With or Without Gout: A Network Meta-Analysis

Front Med (Lausanne). 2021 Jun 15;8:698437. doi: 10.3389/fmed.2021.698437.eCollection 2021.

Shengzhao Zhang 1 2Ting Xu 1 2Qingyang Shi 3Sheyu Li 4 3Ling Wang 2Zhenmei An 4Na Su 1 2


Improving outcomes for patients hospitalised with gout: a systematic review

Rheumatology (Oxford). 2021 Jul 10;keab539. doi: 10.1093/rheumatology/keab539.Online ahead of print.

Mark D Russell 1Benjamin D Clarke 1Edward Roddy 2 3James B Galloway 1


Genetic correlations between traits associated with hyperuricemia, gout, and comorbidities

Eur J Hum Genet. 2021 Feb 26. doi: 10.1038/s41431-021-00830-z. Online ahead of print.

Richard J Reynolds 1M Ryan Irvin 2S Louis Bridges 3Hwasoon Kim 4Tony R Merriman 3 5Donna K Arnett 6Jasvinder A Singh 3 7Nicholas A Sumpter 3Alexa S Lupi 8 9Ana I Vazquez 10 11


The comparative effect of exposure to various risk factors on the risk of hyperuricaemia: diet has a weak causal effect

Arthritis Res Ther. 2021 Mar 4;23(1):75. doi: 10.1186/s13075-021-02444-8.

Ruth K G Topless # 1Tanya J Major # 1Jose C Florez 2 3 4Joel N Hirschhorn 2 5 6Murray Cadzow 1Nicola Dalbeth 7Lisa K Stamp 8Philip L Wilcox 9Richard J Reynolds 10Joanne B Cole # 2 3 5Tony R Merriman # 11 12


Awareness of and reactions to the health harms of sugary drinks: An online study of U.S. parents

Appetite. 2021 Sep 1;164:105234. doi: 10.1016/j.appet.2021.105234. Epub 2021 Apr 3.

Alexandra E Carl 1Lindsey Smith Taillie 2Anna H Grummon 3Allison J Lazard 4Isabella C A Higgins 5Jennifer Mendel Sheldon 6Marissa G Hall 7


Variants in urate transporters, ADH1B, GCKR and MEPE genes associate with transition from asymptomatic hyperuricaemia to gout: results of the first gout versus asymptomatic hyperuricaemia GWAS in Caucasians using data from the UK Biobank

Ann Rheum Dis. 2021 Apr 8;annrheumdis-2020-219796.doi: 10.1136/annrheumdis-2020-219796. Online ahead of print.

Gabriela Sandoval-Plata 1 2 3Kevin Morgan 3Abhishek Abhishek 4 2


Among the Company That Gout Keeps, Is Cancer on the List?

J Rheumatol. 2021 May 15;jrheum.210138. doi: 10.3899/jrheum.210138.Online ahead of print.

Allan C Gelber 1


Allopurinol and Renal Outcomes in Adults With and Without Type 2 Diabetes: A Retrospective, Population-Based Cohort Study and Propensity Score Analysis

Can J Diabetes. 2021 Jan 20;S1499-2671(21)00005-8. doi: 10.1016/j.jcjd.2021.01.005.Online ahead of print.

Alanna Weisman 1George A Tomlinson 2Lorraine L Lipscombe 3Amit X Garg 4Bruce A Perkins 5David Z I Cherney 6Gillian A Hawker 3


Effects of Dietary Patterns on Serum Urate: Results From a Randomized Trial of the Effects of Diet on Hypertension

Arthritis Rheumatol. 2021 Jun;73(6):1014-1020. doi: 10.1002/art.41614. Epub 2021 Apr 23.

Stephen P Juraschek 1Chio Yokose 2Natalie McCormick 2Edgar R Miller 3rd 3Lawrence J Appel 3Hyon K Choi 2


Management and Cure of Gouty Arthritis

Med Clin North Am. 2021 Mar;105(2):297-310. doi: 10.1016/j.mcna.2020.09.013.Epub 2021 Jan 14.

Sarah F Keller 1Brian F Mandell 2


A Randomized Pilot Study of DASH Patterned Groceries on Serum Urate in Individuals with Gout

Nutrients. 2021 Feb 7;13(2):538. doi: 10.3390/nu13020538.

Stephen P Juraschek 1Edgar R Miller 3rd 2Beiwen Wu 2Karen White 2Jeanne Charleston 2Allan C Gelber 2Sharan K Rai 3Kathryn A Carson 2Lawrence J Appel 2Hyon K Choi 4


Potential Association between Kaposi Sarcoma and Gout: An Exploratory Observational Study

Sarcoma. 2020 Dec 1;2020:8844970. doi: 10.1155/2020/8844970. eCollection 2020.

Assaf Moore 1 2Idit Peretz 1Lilach Yosef 1Daniel A Goldstein 1 2Hadar Goldvaser 1 2Suzanna Horn 2 3Yonatan Edel 2 4 5Alona Zer 1 2


Therapeutic Strategies for the Treatment of Chronic Hyperuricemia: An Evidence-Based Update

Medicina (Kaunas). 2021 Jan 10;57(1):58. doi: 10.3390/medicina57010058.

Arrigo F G Cicero 1Federica Fogacci 1Masanari Kuwabara 2Claudio Borghi 1


Post-hoc analysis of pegloticase pivotal trials in chronic refractory gout: relationship between fluctuations in plasma urate levels and acute flares

Clin Exp Rheumatol. 2021 Jan 6. Online ahead of print.

Brian F Mandell 1Theodore R Fields 2N Lawrence Edwards 3Anthony E Yeo 4Peter E Lipsky 5


Hyperuricemia and Cardiovascular Risk

Cureus. 2021 May 5;13(5):e14855. doi: 10.7759/cureus.14855.

Lauren Shahin 1Komal M Patel 1Milad K Heydari 1Marc M Kesselman 1


Gout Flare Burden, Diagnosis, and Management: Navigating Care in Older Patients with Comorbidity

Drugs Aging. 2021 Jun 9. doi: 10.1007/s40266-021-00866-2. Online ahead of print.

Mukund Kumar 1 2Natalie Manley 3Ted R Mikuls 4 5


Gout in Pregnancy: A Rare Phenomenon

Cureus. 2020 Nov 25;12(11):e11697. doi: 10.7759/cureus.11697.

Kevin Pierre 1Noah F Gomez 2Catarina Canha 3Ghania Masri 4


Beyond Arthritis: Understanding the Influence of Gout on Erectile Function: A Systematic Review

Urology. 2020 Dec 17;S0090-4295(20)31492-8. doi: 10.1016/j.urology.2020.12.005.Online ahead of print.

Kyle Park 1Nikhil K Gupta 2Ephrem O Olweny 2Naomi Schlesinger 3


Ultrasonography and dual-energy computed tomography: impact for the detection of gouty deposits

Ultrasonography. 2021 Apr;40(2):197-206. doi: 10.14366/usg.20063. Epub 2020 Oct 2.

Christoph Schwabl 1Mihra Taljanovic 2Gerlig Widmann 1James Teh 3Andrea S Klauser 1



Gout in primary total knee arthroplasty: Prevalent but not independently associated with complications

Knee. 2021 Jan;28:45-50. doi: 10.1016/j.knee.2020.11.007. Epub 2020 Dec 6.

Alexander T Bradley 1Connor A King 2Anna Cohen-Rosenblum 3Peter K Sculco 4David C Landy 5


Contentious Issues in Gout Management: The Story so Far

Open Access Rheumatol. 2021 May 12;13:111-122. doi: 10.2147/OARRR.S282631.eCollection 2021.

Mohamed Talaat 1Kyle Park 1Naomi Schlesinger 2


Limitations of dual-energy CT in the detection of monosodium urate deposition in dense liquid tophi and calcified tophi

Skeletal Radiol. 2021 Feb 2. doi: 10.1007/s00256-021-03715-w. Online ahead of print.

Se Jin Ahn 1Dawen Zhang 2 3Benjamin D Levine 4Nicola Dalbeth 5Bregina Pool 5Veena K Ranganath 6Prosper Benhaim 7Scott D Nelson 8Scott S Hsieh 9John D FitzGerald 7 10


Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes

Am J Cardiovasc Drugs. 2020 Dec 28;1-14. doi: 10.1007/s40256-020-00459-1.Online ahead of print.

Subuhi Kaul 1Manasvi Gupta 2Dhrubajyoti Bandyopadhyay 3Adrija Hajra 4Prakash Deedwania 5Edward Roddy 6Mamas Mamas 7Allan Klein 8Carl J Lavie 9Gregg C Fonarow 10Raktim K Ghosh 11


Identification of Gout Flares in Chief Complaint Text Using Natural Language Processing

AMIA Annu Symp Proc. 2021 Jan 25;2020:973-982. eCollection 2020.

John D Osborne 1James S Booth 1Tobias O'Leary 1Amy Mudano 1Giovanna Rosas 1Phillip J Foster 1Kenneth G Saag 1Maria I Danila 1


Assessing the Causal Relationships between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization

Arthritis Rheumatol. 2021 May 13. doi: 10.1002/art.41779. Online ahead of print.

Natalie McCormick 1 2 3 4Mark J O'Connor 5Chio Yokose 1 2 3Tony R Merriman 6 7David B Mount 3 8Aaron Leong 3 9 10 11Hyon K Choi 1 2 3 4


The incidence and prevalence of cardiovascular diseases in gout: a systematic review and meta-analysis

Rheumatol Int. 2021 May 13. doi: 10.1007/s00296-021-04876-6. Online ahead of print.

Peter Cox 1Sonal Gupta 2Sizheng Steven Zhao 3David M Hughes 4


Anti-inflammatory therapy for COVID-19 infection: the case for colchicine

Ann Rheum Dis. 2020 Dec 8;annrheumdis-2020-219174.doi: 10.1136/annrheumdis-2020-219174. Online ahead of print.

Aaron Z Reyes 1Kelly A Hu 1Jacob Teperman 1Theresa L Wampler Muskardin 2 3Jean-Claude Tardif 4Binita Shah 5 6Michael H Pillinger 7 8


Characteristics, Comorbidities, and Potential Consequences of Uncontrolled Gout: An Insurance-Claims Database Study

Rheumatol Ther. 2021 Mar;8(1):183-197. doi: 10.1007/s40744-020-00260-1. Epub 2020 Dec 7.

Megan Francis-Sedlak 1Brian LaMoreaux 2Lissa Padnick-Silver 2Robert J Holt 2Alfonso E Bello 3


Wastewater-based prevalence trends of gout in an Australian community over a period of 8 years

Sci Total Environ. 2021 Mar 10;759:143460. doi: 10.1016/j.scitotenv.2020.143460.Epub 2020 Nov 9.

Fahad Ahmed 1Benjamin Tscharke 2Jake W O'Brien 2Qiuda Zheng 2Jack Thompson 2Jochen F Mueller 2Kevin V Thomas 2


Effect of Intensive Urate Lowering With Combined Verinurad and Febuxostat on Albuminuria in Patients With Type 2 Diabetes: A Randomized Trial

Am J Kidney Dis. 2021 Apr;77(4):481-489.doi: 10.1053/j.ajkd.2020.09.009. Epub 2020 Oct 29.

Austin G Stack 1Nalina Dronamraju 2Joanna Parkinson 3Susanne Johansson 3Eva Johnsson 3Fredrik Erlandsson 3Robert Terkeltaub 4


Designing a Strategy Trial for the Management of Gout: the use of a Modified Delphi Panel

ACR Open Rheumatol. 2021 May 1. doi: 10.1002/acr2.11243. Online ahead of print.

Daniel H Solomon 1Joel S Weissman 1Hyon Choi 2Steven J Atlas 2Cesar Berardinelli 3Julien Dedier 4Michael A Fischer 1John Fitzgerald 5Erica Hinteregger 1Brianne Johnsen 2Diana D Marini 3Robert McLean 6Fred Murray 3Tuhina Neogi 4Lynn B Oertel 2Michael H Pillinger 7Kevin R Riggs 8Ken Saag 8Dong Suh 1James Watkins 3Michael J Barry 2


Gout, Rheumatoid Arthritis, and the Risk of Death Related to Coronavirus Disease 2019: An Analysis of the UK Biobank

ACR Open Rheumatol. 2021 Apr 15. doi: 10.1002/acr2.11252. Online ahead of print.

Ruth K Topless 1Amanda Phipps-Green 1Megan Leask 2Nicola Dalbeth 3Lisa K Stamp 4Philip C Robinson 5Tony R Merriman 2


Epidemiology and Outcomes of Alcohol Use Hospitalizations in People With Gout, Rheumatoid Arthritis, Fibromyalgia, Osteoarthritis, or Low Back Pain: A National US Study

J Clin Rheumatol. 2021 Mar 25. doi: 10.1097/RHU.0000000000001731. Online ahead of print.

Jasvinder A Singh 1


A neutrophil signature is strongly associated with increased cardiovascular risk in gout

Rheumatology (Oxford). 2020 Nov 14;keaa712. doi: 10.1093/rheumatology/keaa712.Online ahead of print.

Daisy Vedder 1 2Martijn Gerritsen 1Michael T Nurmohamed 1 2 3Ronald F van Vollenhoven 1 3Christian Lood 4


Estimation of Primary Prevention of Gout in Men Through Modification of Obesity and Other Key Lifestyle Factors

JAMA Netw Open. 2020 Nov 2;3(11):e2027421.doi: 10.1001/jamanetworkopen.2020.27421.

Natalie McCormick 1 2 3 4Sharan K Rai 4 5Na Lu 4 6Chio Yokose 1 2 3Gary C Curhan 6 7Hyon K Choi 1 2 3 4


Something Old, Something New: the ACR Gout Treatment Guideline and Its Evolution from 2012 to 2020

Rebecca E Cohen 1Michael H Pillinger 1 2Michael Toprover 3 4 5


Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial

Lancet. 2020 Nov 28;396(10264):1745-1757.doi: 10.1016/S0140-6736(20)32234-0. Epub 2020 Nov 9.

Isla S Mackenzie 1Ian Ford 2George Nuki 3Jesper Hallas 4Christopher J Hawkey 5John Webster 6Stuart H Ralston 7Matthew Walters 8Michele Robertson 2Raffaele De Caterina 9Evelyn Findlay 1Fernando Perez-Ruiz 10John J V McMurray 8Thomas M MacDonald 11FAST Study Group


FAST Study Group: 

J AzizG DobsonA S F DoneyR W V FlynnJ FurnaceJ W K GrieveG GuthrieD JamiesonC G JenningsS KeanL C LundA McConnachieF PigazzaniP L RichesM Rix HansonA RogersE D M RookeJ ThomsonM WarrenK WetherallR WilsonC P HallA MaseriH A BirdG MurrayJ W DearM PetrieM MacDonaldP S JhundE ConnollyD J MurphyN PaulA OlssonP T KoskinenA FuatA FosterW SaywoodR J BarrL McConnachieL F WilsonL Larsen RasmussenA R McGinnisH BirrellM KeillerI S BremnerG J ForbesJ S DumbletonJ RhodesT Waller


The Epidemiology and Genetics of Hyperuricemia and Gout across Major Racial Groups: A Literature Review and Population Genetics Secondary Database Analysis

J Pers Med. 2021 Mar 22;11(3):231. doi: 10.3390/jpm11030231.

Faven Butler 1Ali Alghubayshi 1Youssef Roman 1


Gout: Rapid Evidence Review

Am Fam Physician. 2020 Nov 1;102(9):533-538.

Karl T Clebak 1Ashley Morrison 1Jason R Croad 1


Puzzling Out the Colchicine Biosynthetic Pathway

ChemMedChem. 2021 Feb 17;16(4):621-623. doi: 10.1002/cmdc.202000633.Epub 2020 Nov 9.

Emily A Stander 1Nicolas Papon 2 3Vincent Courdavault 1


Management of Rheumatic Diseases During the COVID-19 pandemic: A National Veterans Affairs Survey of Rheumatologists

Arthritis Care Res (Hoboken). 2020 Oct 15;10.1002/acr.24487. doi: 10.1002/acr.24487.Online ahead of print.

Jasvinder A Singh 1 2 3John S Richards 4Elizabeth Chang 5Amy Joseph 6 7Bernard Ng 8 9


Allopurinol use and type 2 diabetes incidence among patients with gout: A VA retrospective cohort study

Medicine (Baltimore). 2020 Aug 28;99(35):e21675.doi: 10.1097/MD.0000000000021675.

Anastasia Slobodnick 1 2Michael Toprover 1 2Jeffrey Greenberg 2Daria B Crittenden 2Virginia C Pike 1 2Yingzhi Qian 3Hua Zhong 3Michael H Pillinger 1 2


Latent Class Growth Analysis of Gout Flare Trajectories: A Three-Year Prospective Cohort Study in Primary Care

Arthritis Rheumatol. 2020 Nov;72(11):1928-1935. doi: 10.1002/art.41476. Epub 2020 Oct 3.

Lorraine Watson 1John Belcher 1Elaine Nicholls 1 2Sara Muller 1Christian Mallen 1 3 4Edward Roddy 1 3


Rebranding Gout: Could a Name Change for Gout Improve Adherence to Urate-Lowering Therapy?

Ther Innov Regul Sci. 2021 Jan;55(1):138-141. doi: 10.1007/s43441-020-00198-0.Epub 2020 Jul 13.

Matthew J Coleshill 1 2Eindra Aung 3 4Jane E Carland 3 4Kate Faasse 5Sophie Stocker 3 4Richard O Day 3 4


Use of electronic recruitment methods in a clinical trial of adults with gout

Clin Trials. 2021 Feb;18(1):92-103. doi: 10.1177/1740774520956969. Epub 2020 Sep 15.

Hailey N Miller 1 2Jeanne Charleston 2 3Beiwen Wu 3Kelly Gleason 1 2Karen White 3Cheryl R Dennison Himmelfarb 1 2Daniel E Ford 2 3Timothy B Plante 4Allan C Gelber 3 5Lawrence J Appel 2 3 5Edgar R Miller 3rd 2 3 5Stephen P Juraschek 6


Pegloticase in Combination With Methotrexate in Patients With Uncontrolled Gout: A Multicenter, Open-label Study (MIRROR)

J Rheumatol. 2020 Sep 15;jrheum.200460. doi: 10.3899/jrheum.200460. Online ahead of print.

John K Botson 1John R P Tesser 1Ralph Bennett 1Howard M Kenney 1Paul M Peloso 1Katie Obermeyer 1Brian LaMoreaux 1Michael E Weinblatt 1Jeff Peterson 1


Cardiovascular safety risks associated with gout treatments

Expert Opin Drug Saf. 2020 Sep;19(9):1143-1154.doi: 10.1080/14740338.2020.1804551. Epub 2020 Aug 12.

Giovanna Rosas 1Angelo Gaffo 1Elizabeth J Rahn 1Kenneth G Saag 1


Increased Efficacy and Tolerability of Pegloticase in Patients With Uncontrolled Gout Co-Treated With Methotrexate: A Retrospective Study

Rheumatol Ther. 2020 Sep;7(3):639-648. doi: 10.1007/s40744-020-00222-7. Epub 2020 Jul 27.

John A Albert 1Tony Hosey 2Brian LaMoreaux 2


Interventions to improve uptake of urate-lowering therapy in patients with gout: a systematic review

BJGP Open. 2020 Aug 25;4(3):bjgpopen20X101051. doi: 10.3399/bjgpopen20X101051.Print 2020 Aug.

Iqbal Gill 1Nicola Dalbeth 2Malakai 'Ofanoa 3Felicity Goodyear-Smith 4


Therapeutic approaches in the treatment of gout

Semin Arthritis Rheum. 2020 Jun;50(3S):S24-S30.doi: 10.1016/j.semarthrit.2020.04.010.

Michael H Pillinger 1Brian F Mandell 2


The experience of a gout flare: a meta-synthesis of qualitative studies

Semin Arthritis Rheum. 2020 Aug;50(4):805-811.doi: 10.1016/j.semarthrit.2020.06.001. Epub 2020 Jun 9.

Sarah Stewart 1Andrea Garcia Guillen 2William J Taylor 3Angelo Gaffo 4Julia Slark 5Merryn Gott 6Nicola Dalbeth 7


Article placement order in rheumatology journals: a content analysis

BMJ Open. 2020 Jun 17;10(6):e034550. doi: 10.1136/bmjopen-2019-034550.

Sarah Stewart 1Greg Gamble 1Andrew Grey 1Nicola Dalbeth 2


Colchicine Prophylaxis of Gout Flares When Commencing Allopurinol is Very Cost Effective

Arthritis Care Res (Hoboken). 2020 Jun 17. doi: 10.1002/acr.24357. Online ahead of print.

Philip C Robinson 1 2Nicola Dalbeth 3Peter Donovan 1 2


Changing paradigms in the management of gout

J R Coll Physicians Edinb. 2020 Jun;50(2):124-132. doi: 10.4997/JRCPE.2020.209.

George Nuki 1Philip Riches 2


Development of a multivariable improvement measure for gout

Arthritis Res Ther. 2020 Jun 29;22(1):164. doi: 10.1186/s13075-020-02254-4.

Naomi Schlesinger 1N Lawrence Edwards 2Anthony E Yeo 3Peter E Lipsky 4


2020 American College of Rheumatology Guideline for the Management of Gout

Arthritis Care Res (Hoboken). 2020 Jun;72(6):744-760.doi: 10.1002/acr.24180. Epub 2020 May 11.

John D FitzGerald 1Nicola Dalbeth 2Ted Mikuls 3Romina Brignardello-Petersen 4Gordon Guyatt 4Aryeh M Abeles 5Allan C Gelber 6Leslie R Harrold 7Dinesh Khanna 8Charles King 9Gerald Levy 10Caryn Libbey 11David Mount 12Michael H Pillinger 5Ann Rosenthal 13Jasvinder A Singh 14James Edward Sims 15Benjamin J Smith 16Neil S Wenger 17Sangmee Sharon Bae 17Abhijeet Danve 18Puja P Khanna 19Seoyoung C Kim 20Aleksander Lenert 21Samuel Poon 22Anila Qasim 4Shiv T Sehra 23Tarun Sudhir Kumar Sharma 24Michael Toprover 5Marat Turgunbaev 25Linan Zeng 4Mary Ann Zhang 20Amy S Turner 25Tuhina Neogi 11


Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout

Arthritis Res Ther. 2020 Mar 12;22(1):45. doi: 10.1186/s13075-020-2136-z.

Rebekah Wrigley 1Amanda J Phipps-Green 1Ruth K Topless 1Tanya J Major 1Murray Cadzow 1Philip Riches 2Anne-Kathrin Tausche 3Matthijs Janssen 4Leo A B Joosten 5 6Tim L Jansen 4Alexander So 7Jennie Harré Hindmarsh 8Lisa K Stamp 9Nicola Dalbeth 10Tony R Merriman 11


Immunosuppressant Use and Gout in the Prevalent Solid Organ Transplantation Population

Prog Transplant. 2020 Jun;30(2):103-110. doi: 10.1177/1526924820913514. Epub 2020 Mar 25.

Mark D Brigham 1Andrew Milgroom 1Mara Onita Lenco 1Zheng Wang 1Jeffrey D Kent 2Brian LaMoreaux 2Richard J Johnson 3Brian F Mandell 4Nandini Hadker 1Herman Sanchez 1Kevin Francis 1Lauren P Radeck 1Gavin Miyasato 1Justin W Li 1


Allopurinol hypersensitivity: Pathogenesis and prevention

Best Pract Res Clin Rheumatol. 2020 Aug;34(4):101501.doi: 10.1016/j.berh.2020.101501. Epub 2020 Apr 4.

Lisa K Stamp 1Peter T Chapman 2


C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1

Sci Rep. 2020 Apr 14;10(1):6391. doi: 10.1038/s41598-020-63318-8.

Anika Alberts 1Annika Klingberg 1Anne Kathrin Wessig 1Christèle Combes 2Torsten Witte 3Korbinian Brand 1Andreas Pich 4Konstantin Neumann 5


2020 American College of Rheumatology Guideline for the Management of Gout

Arthritis Rheumatol. 2020 Jun;72(6):879-895. doi: 10.1002/art.41247.Epub 2020 May 11.

John D FitzGerald 1, Nicola Dalbeth 2, Ted Mikuls 3, Romina Brignardello-Petersen 4, Gordon Guyatt 4, Aryeh M Abeles 5, Allan C Gelber 6, Leslie R Harrold 7, Dinesh Khanna 8, Charles King 9, Gerald Levy 10, Caryn Libbey 11, David Mount 12, Michael H Pillinger 5, Ann Rosenthal 13, Jasvinder A Singh 14, James Edward Sims 15, Benjamin J Smith 16, Neil S Wenger 17, Sangmee Sharon Bae 17, Abhijeet Danve 18, Puja P Khanna 19, Seoyoung C Kim 20, Aleksander Lenert 21, Samuel Poon 22, Anila Qasim 4, Shiv T Sehra 23, Tarun Sudhir Kumar Sharma 24, Michael Toprover 5, Marat Turgunbaev 25, Linan Zeng 4, Mary Ann Zhang 20, Amy S Turner 25, Tuhina Neogi 11


Effect of Bempedoic Acid on Serum Uric Acid and Related Outcomes: A Systematic Review and Meta-analysis of the available Phase 2 and Phase 3 Clinical Studies

Drug Saf. 2020 Aug;43(8):727-736. doi: 10.1007/s40264-020-00931-6.

Arrigo F G Cicero 1, Roberto Pontremoli 2, Federica Fogacci 3, Francesca Viazzi 2, Claudio Borghi 3


Flare Rate Thresholds for Patient Assessment of Disease Activity States in Gout

J Rheumatol. 2020 May 1;jrheum.191242. doi: 10.3899/jrheum.191242. Online ahead of print.

William Taylor 1, Nicola Dalbeth 1, Kenneth G Saag 1, Jasvinder A Singh 1, Elizabeth J Rahn 1, Amy S Mudano 1, Yi-Hsing Chen 1, Ching-Tsai Lin 1, Paul Tan 1, Worawit Louthreno 1, Janitzia Vazquez-Mellado 1, Hansel Hernández-Llinas 1, Tuhina Neogi 1, Ana B Vargas-Santos 1, Geraldo Castelar-Pinheiro 1, Rodrigo B Chaves-Amorim 1, Tillman Uhlig 1, Hilde B Hammer 1, Maxim Eliseev 1, Fernando Perez-Ruiz 1, Lorenzo Cavagna 1, Geraldine M McCarthy 1, Lisa K Stamp 1, Martijin Gerritsen 1, Viktoria Fana 1, Francisca Sivera 1, Angelo L Gaffo 1


Lessons and pitfalls from the 2020 Gout Clinical Practice Guideline presented in Atlanta at the ACR 2019

Clin Rheumatol. 2020 Jun;39(6):2011-2016. doi: 10.1007/s10067-020-05070-y.Epub 2020 Apr 21.

Tim L Jansen 1, Matthijs Janssen 2


Mortality in patients with gout treated with allopurinol: a systematic review and meta-analysis

Arthritis Care Res (Hoboken). 2020 Apr 14. doi: 10.1002/acr.24205. Online ahead of print.

Charles A Hay 1, James A Prior 1, John Belcher 1, Christian D Mallen 1, Edward Roddy 1


Hypersensitivity reactions with allopurinol and febuxostat: a study using the Medicare claims data

Ann Rheum Dis. 2020 Apr;79(4):529-535. doi: 10.1136/annrheumdis-2019-216917.Epub 2020 Feb 5.

Jasvinder A Singh 1 2, John D Cleveland 3


Management of Gout in the United States: A Claims-based Analysis

ACR Open Rheumatol. 2020 Mar;2(3):180-187. doi: 10.1002/acr2.11121. Epub 2020 Mar 1

N Lawrence Edwards 1, Naomi Schlesinger 2, Sanders Clark 3, Theresa Arndt 3, Peter E Lipsky 4


Epidemiology of Depression and Anxiety in Gout: A Systematic Review and Metaanalysis

J Rheumatol. 2021 Jan 1;48(1):129-137. doi: 10.3899/jrheum.190974. Epub 2020 Mar 1.

Alyssa Howren 1, Drew Bowie 2, Hyon K Choi 3, Sharan K Rai 4, Mary A De Vera 5